Research Articles

While you can easily go to google scholar to look up pages, and pages, of great research showing the posive benefits of our health treatments, and Lifestyle Therapy (therapeutic lifestyle change programs) we have collected a few for you here.

As one of the first providers of PBM, Molecular Hydrogen and other cutting edge therapies in the area, we researched extensively to make sure you got the best. We are pleased to have been successfully providing quality, cutting-edge health treatments with amazing results since 2018. 

Prior to cutting-edge health treatments, Bliss Lifestyle Therapies professionals have been providing powerful, successful, therapeutic lifestyle change programs since 1997.

Lifestyle Therapy

Implicit theories of well-being predict well-being and the endorsement of therapeutic lifestyle changes — Journal of Happiness Studies, 2015.

Prevent or reverse Hypertension, Hyperlipidemia, and Cardiovascular Disease

Primary care-led weight management for remission of type 2 diabetes (DiRECT) — The Lancet, 2018. Nearly half of participants put type 2 diabetes into remission within a year.

5-year follow-up of the Diabetes Remission Clinical Trial (DiRECT) — The Lancet Diabetes & Endocrinology. Shows how remission holds up over five years with continued support.

Intensive lifestyle changes for reversal of coronary heart disease — JAMA, 1998. Heart artery blockages shrank with lifestyle changes alone.

Effects on blood pressure of reduced dietary sodium and the DASH diet — New England Journal of Medicine, 2001. Diet changes lowered blood pressure within weeks.

Primary prevention of cardiovascular disease with a Mediterranean diet (PREDIMED) — New England Journal of Medicine, 2018. A Mediterranean-style diet lowered heart attack and stroke risk.

Therapeutic lifestyle changes for cardiovascular disease — The Physician and Sportsmedicine, 2012.

Impact of therapeutic lifestyle changes in resistant hypertension — Progress in Cardiovascular Diseases, 2020.

Effectiveness of therapeutic lifestyle changes in patients with hypertension, hyperlipidemia, and/or hyperglycemia— The American Journal of Cardiology, 2004.

Prevalence and profile of metabolic syndrome in patients following acute coronary events and effects of therapeutic lifestyle change with cardiac rehabilitation — The American Journal of Cardiology, 2003.

Effect of comprehensive therapeutic lifestyle changes on prehypertension — The American Journal of Cardiology, 2008.

Simvastatin vs therapeutic lifestyle changes and supplements: randomized primary prevention trial — Mayo Clinic Proceedings, 2008.

Therapies for diabetic dyslipidaemia — Diabetes, Obesity and Metabolism, 2011.

Effects of a therapeutic lifestyle-change programme on cardiac risk factors after coronary artery bypass graft — Journal of Clinical Nursing, 2009.

Prevent or reverse Type II Diabetes

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin — New England Journal of Medicine, 2002. Lifestyle changes cut new type 2 diabetes cases by 58%, more than the drug metformin.

Therapeutic lifestyle changes for diabetes mellitus — Nursing Clinics of North America, 2017.

Weight management through lifestyle modification for the prevention and management of type 2 diabetes: rationale and strategies (American Diabetes Association statement) — American Journal of Clinical Nutrition, 2004.

Change in glycemic control with use of a digital therapeutic in adults with type 2 diabetes: cohort study — JMIR Diabetes, 2018.

Effectiveness of therapeutic lifestyle changes in patients with hypertension, hyperlipidemia, and/or hyperglycemia — The American Journal of Cardiology, 2004.

Therapeutic lifestyle changes improve HDL function by inhibiting myeloperoxidase-mediated oxidation in patients with metabolic syndrome — Diabetes Care, 2018.

 

PBM Benefits (Photobiomodulation aka light therapy)

Detoxification:

Sauna use as a lifestyle practice to extend healthspan — Experimental Gerontology, 2021.

Physical Performance Benefits:

Can pre-exercise photobiomodulation improve muscle endurance and promote recovery? A meta-analysis of randomized controlled trials — Lasers in Medical Science, 2024.

Endocrine effects of repeated sauna bathing — Acta Physiologica Scandinavica, 1986.

Healing Brain and Mood:

Shining light on the head: photobiomodulation for brain disorders — BBA Clinical, 2016. A free overview by Michael Hamblin of how NIR light reaches and supports the brain.

Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies — Ageing Research Reviews, 2022.

Transcranial photobiomodulation increases cognition and serum BDNF levels in adults over 50 years: a randomized, double-blind, placebo-controlled trial — Journal of Photochemistry and Photobiology B: Biology, 2024.

Photobiomodulation improves depression symptoms: a systematic review and meta-analysis of randomized controlled trials — Frontiers in Psychiatry, 2024. Free to read.

Immune Boosting:

Heat shock proteins and immunity: application of hyperthermia for immunomodulation — International Journal of Hyperthermia, 2009. Helps strengthen your defenses.

Improved Weight Loss:

Fat loss by red and near infrared LED phototherapy — Mechanisms of Photobiomodulation Therapy XIV (SPIE), 2019.

Clinical implications of thermal therapy in lifestyle-related diseases — Experimental Biology and Medicine, 2003. Helps obese people lose body weight and mass.

Skin and subcutaneous fat morphology alterations under the LED or laser treatment in rats in vivo — Journal of Biophotonics, 2019.

Stress Reduction:

Transcranial low-level laser therapy for depression and Alzheimer’s disease — Neuropsychiatry, 2018. Helps boost natural feel-good brain chemistry.

Skin Rejuvination:

A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase — Photomedicine and Laser Surgery, 2014. Shown to boost collagen and elastin.

Pain Relief:

Effectiveness of photobiomodulation in reducing pain and disability in patients with knee osteoarthritis: a systematic review with meta-analysis — Physical Therapy, 2024.

Infrared therapy for chronic low back pain: a randomized, controlled trial — Pain Research & Management, 2006. Helps joint and muscle pain sufferers find natural relief.

Longevity:

Association between sauna bathing and fatal cardiovascular and all-cause mortality events — JAMA Internal Medicine, 2015. Reduced heart attack risk.

Wound Healing:

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation — AIMS Biophysics, 2017. A free, plain overview by Michael Hamblin of Harvard, a leading PBM researcher.

Photobiomodulation using red and infrared LED for the healing of diabetic foot ulcers: a controlled randomized clinical trial — Lasers in Medical Science, 2024.

Red light-emitting diode (LED) therapy accelerates wound healing post-blepharoplasty and periocular laser ablative resurfacing — Journal of Cosmetic and Laser Therapy, 2006.

Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice — Journal of Clinical Laser Medicine & Surgery, 2003.

Organic light emitting diode improves diabetic cutaneous wound healing in rats — Wound Repair and Regeneration, 2015.

Improved Mitochondrial Function:

Clinical and experimental applications of NIR-LED photobiomodulation — Photomedicine and Laser Surgery, 2006.

Improved Blood Sugar Handling and Insulin:

Infrared photobiomodulation (PBM) therapy improves glucose metabolism and intracellular insulin pathway in adipose tissue of high-fat fed mice — Lasers in Medical Science, 2017.

Molecular Hydrogen (H2)

Research suggests that all body systems benefit from the powerful antioxidant effects of H2

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals — Nature Medicine, 2007. The study that started hydrogen medicine research.

Beneficial biological effects and the underlying mechanisms of molecular hydrogen: comprehensive review of 321 original articles — Medical Gas Research, 2015. A free summary of hundreds of studies.

Molecular hydrogen therapy: a review on clinical studies and outcomes — Molecules, 2023. A free summary of human clinical studies.

Hydrogen water: extra healthy or a hoax? A systematic review — International Journal of Molecular Sciences, 2024. A balanced, free review of the evidence.

Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance — Nutrition Research, 2008.

The effects of 24-week, high-concentration hydrogen-rich water on body composition, blood lipid profiles and inflammation biomarkers in men and women with metabolic syndrome: a randomized controlled trial — Diabetes, Metabolic Syndrome and Obesity, 2020. Free to read.

Can molecular hydrogen supplementation enhance physical performance in healthy adults? A systematic review and meta-analysis — 2024.

Effect of hydrogen–oxygen inhalation on sleep disorders and abnormal mood: a single-blind, randomized controlled trial — Medical Gas Research, 2025.

Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases — Oxidative Medicine and Cellular Longevity, 2012.

Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine — Pharmacology & Therapeutics, 2014.

Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications — Methods in Enzymology, 2015.

Molecular hydrogen in sports medicine: new therapeutic perspectives — International Journal of Sports Medicine, 2014.

Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications — Current Pharmaceutical Design, 2011.

Microcirculation

Energy and Recovery

Effect of BEMER magnetic field therapy on the level of fatigue in patients with multiple sclerosis: a randomized, double-blind controlled trial — Journal of Alternative and Complementary Medicine, 2009.

Microcirculatory effects of pulsed electromagnetic fields — Journal of Orthopaedic Research, 2004. A lab study showing PEMF widened small blood vessels and increased blood flow.

A literature review: the effects of magnetic field exposure on blood flow and blood vessels in the microvasculature— Bioelectromagnetics, 2007. Summarizes research on magnetic fields and microcirculation.

Treatment of patients with multiple organ dysfunction syndrome with an electromagnetic field coupled to biorhythmically defined impulse configuration (MicrocircMODS) — Clinical Research in Cardiology, 2023. A clinical trial of a BEMER-type field in hospital patients.

The impact of pulsed electromagnetic field therapy on blood pressure and circulating nitric oxide levels — Blood Pressure, 2019. A double-blind trial in people with metabolic syndrome.

Effects of pulsed electromagnetic field therapy on pain, stiffness and physical function in patients with knee osteoarthritis: a systematic review and meta-analysis — Journal of Rehabilitation Medicine, 2020. Pooled controlled trials found improvements in pain and physical function.

Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: a systematic review and meta-analysis — Clinical Rehabilitation, 2022.

Assessing the effects of pulsed electromagnetic therapy on painful diabetic peripheral neuropathy: a double-blind randomized controlled trial — Journal of Diabetes Science and Technology, 2023.

The effects of “physical BEMER vascular therapy” on work performed during repeated Wingate sprints — Research Quarterly for Exercise and Sport, 2022.

Improved circulation for wound healing

The effects of the “physical BEMER vascular therapy” on sleep, pain and quality of life of patients with different clinical pictures — Journal of Complementary and Integrative Medicine, 2013.

The technological development history and current significance of the “physical BEMER vascular therapy” in medicine — Journal of Complementary and Integrative Medicine, 2013.

Cardiovascular benefits

Physical vascular therapy (BEMER) affects heart rate asymmetry in patients with coronary heart disease — In Vivo, 2022.

Relief from musculoskeletal diseases

BEMER therapy combined with physiotherapy in patients with musculoskeletal diseases: a randomised, controlled double blind follow-up pilot study — Evidence-Based Complementary and Alternative Medicine, 2015.

Thermotherapy (heat via NIR & FIR)

Association between sauna bathing and fatal cardiovascular and all-cause mortality events — JAMA Internal Medicine, 2015. Frequent sauna use was linked to fewer heart-related deaths over 20 years.

Cardiovascular and other health benefits of sauna bathing: a review of the evidence — Mayo Clinic Proceedings, 2018.

Waon therapy improves the prognosis of patients with chronic heart failure — Journal of Cardiology, 2009. Far-infrared heat therapy in heart failure patients.

Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors — Journal of the American College of Cardiology, 2001. Far-infrared sauna sessions improved blood vessel function.

Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure— Journal of the American College of Cardiology, 2002.

Clinical effects of regular dry sauna bathing: a systematic review — Evidence-Based Complementary and Alternative Medicine, 2018. Reviews traditional and infrared sauna studies.

Far infrared radiation (FIR): its biological effects and medical applications — Photonics & Lasers in Medicine, 2012.

Immune boosting, and COVID 19 recovery

Turning up the heat on COVID-19: heat as a therapeutic intervention — F1000Research, 2020.

Improved quality of life and improvements in type II diabetes 

Whole-body hyperthermia for the treatment of major depressive disorder: a randomized clinical trial — JAMA Psychiatry, 2016. A single session of whole-body infrared heating reduced depression symptoms for weeks.

Do far-infrared saunas have cardiovascular benefits in people with type 2 diabetes? — Canadian Journal of Diabetes, 2009.

The effects of repeated thermal therapy on quality of life in patients with type II diabetes mellitus — The Journal of Alternative and Complementary Medicine, 2010.

Reduced menopausal symptoms and improved bone density

Local thermal therapy effects on menopausal symptoms and bone mineral density — The Journal of Alternative and Complementary Medicine, 2011.

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